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Index > Protein center > UCN2(Gene name) > Human
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  • UCN2 (Gene name),
  • Urocortin-2 (Protein name ),  UCN2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UCN2(SRP;URP);
    Protein name:
    Urocortin-2;
    Alternative:
    Urocortin II(Ucn II);Stresscopin-related peptide;Urocortin-related peptide;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds with high affinity to CRF receptors 2-alpha and 2-beta.
    Function:
    Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    112
    Sequence:
    50:
    MTRCALLLLM | VLMLGRVLVV | PVTPIPTFQL | RPQNSPQTTP | RPAASESPSA | 
    100:
    APTWPWAAQS | HCSPTRHPGS | RIVLSLDVPI | GLLQILLEQA | RARAAREQAT | 
    112:
    TNARILARVG | HC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Urocortin-2
    Cat.:
    E1445h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Urocortin-2
    Cat.:
    E1445m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Urocortin-2
    Cat.:
    E1445r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin-2
    Cat.:
    U1445r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin-2
    Cat.:
    U1445m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Urocortin-2
    Cat.:
    U1445h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Urocortin-2
    Cat.:
    P1445Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Urocortin-2
    Cat.:
    P1445Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Urocortin-2
    Cat.:
    P1445Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Urocortin-2
    Monoclonal Antibody for Human Urocortin-2
    Monoclonal Antibody for Human Urocortin-2
    Protein for Human Urocortin-2
    Protein for Human Urocortin-2
    Protein for Human Urocortin-2

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    Linearity
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    References
    1. 1.
      "Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor."
      Hsu S.Y. , Hsueh A.J.W.
      Nat. Med.7:605-611(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
      tissue: Uterus.
    3. 3.
      "Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products."
      Vaughan J.M. , Donaldson C.J. , Fischer W.H. , Perrin M.H. , Rivier J.E. , Sawchenko P.E. , Vale W.W.
      Endocrinology154:1553-1564(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LACK OF AMIDATION
    4. 4.
      "Common and divergent structural features of a series of corticotropin releasing factor-related peptides."
      Grace C.R.R. , Perrin M.H. , Cantle J.P. , Vale W.W. , Rivier J.E. , Riek R.
      J. Am. Chem. Soc.129:16102-16114(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 72-109
    5. 5.
      "Structural basis for hormone recognition by the Human CRFR2{alpha} G protein-coupled receptor."
      Pal K. , Swaminathan K. , Xu H.E. , Pioszak A.A.
      J. Biol. Chem.285:40351-40361(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.72 ANGSTROMS) OF 94-109 IN COMPLEX WITH CRHR2
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